Arbor Vita Overview
Arbor Vita's goal is to become the leader in developing first-in-class PDZ-directed therapeutics and diagnostics. In addition to internal product development, the company's business strategy includes out-licensing diagnostic products and other proprietary technologies as well as utilizing strategic partnerships to facilitate drug discovery and commercialization. Recent studies in animals have...More»
Arbor Vita's goal is to become the leader in developing first-in-class PDZ-directed therapeutics and diagnostics. In addition to internal product development, the company's business strategy includes out-licensing diagnostic products and other proprietary technologies as well as utilizing strategic partnerships to facilitate drug discovery and commercialization. Recent studies in animals have shown PDZ-based therapeutics, working inside the cell, to be efficacious in a setting where conventional drugs have failed due to intolerable side effects. These studies demonstrated that PDZ proteins are a new class of drug target, operating inside the cells, which are amenable to regulation using drugs. PDZ proteins are important in numerous human diseases and are just being recognized as an ideal human drug target.«Less
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| Name: | NA-1 Stroke |
| Product URL: | http://www.arborvita.com/products_NA1.html |
| Description: | NA-1 binds to a PDZ protein and disrupts the cell signaling pathway which initiates and continues cell death after a stroke. In results from studies in laboratory rats, NA-1 has been found to reduce the brain damage that occurs during a stroke by as much as 80%. In partnership with another biotech company, a Phase I clinical trial is planned for mid-2006. |
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