NeuroDerm Overview
NeuroDerm developed ND0601, the first ever levodopa (L-DOPA) skin patch for Parkinson’s disease. This passive, non-invasive system is based on a proprietary L-DOPA ester formulation. ND0601 is able to achieve continuous delivery of L-DOPA, an objective that was long considered the “holy grail” of Parkinson’s disease treatment.
By overcoming the short half life of orally administered L-Dopa, the...More»
NeuroDerm developed ND0601, the first ever levodopa (L-DOPA) skin patch for Parkinson’s disease. This passive, non-invasive system is based on a proprietary L-DOPA ester formulation. ND0601 is able to achieve continuous delivery of L-DOPA, an objective that was long considered the “holy grail” of Parkinson’s disease treatment.
By overcoming the short half life of orally administered L-Dopa, the company hopes to minimize or even reverse some of the disabling late motor complications associated with the current L-DOPA oral administration. Moreover, by providing newly diagnosed patients with low, continuous levels of L-Dopa the company hopes to be able to prevent or significantly delay the later emergence of dyskinesia and other late stage motor complications. ND0601 has already entered clinical and regulatory development and the company hopes to eventually be able to offer a solution to motor complications affecting millions of PD patients.«Less
Funding
| Date | Type | Capital Amount | Post-Money Valuation | Investors |
|---|---|---|---|---|
| 07/2007 | Series A | 2.5M | Unknown |
Products
| Name: | ND0601 |
| Product URL: | http://www.neuroderm.co.il/rdip.html |
| Description: | ND0601 Is being developed to be worn 24 hours in order to achieve a constant, therapeutic level of L-Dopa in the blood. A first human pilot pK trial, measuring L-DOPA blood levels for 24 hours, was completed at the end of 2006. Based on discussions with regulatory authorities, it is anticipated that the product should benefit from a lenient clinical development route. This product as well as NeuroDerm’s other intellectual property are protected by strong, wide-scope issued patents covering both the formulation and the transdermal delivery of all L-DOPA alkyl esters. |
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